Publications
Research articles
2021
Wiedemann GM, Santosa EK, Grassmann S, Sheppard S, Le Luduec JB, Adams NM, Dang C, Hsu KC, Sun JC**, Lau CM**. Deconvoluting global cytokine signaling networks in natural killer cells. Nat Immunol. 2021 May;22(5):627-638. doi: 10.1038/s41590-021-00909-1. Epub 2021 Apr 15. PubMed PMID: 33859404; PubMed Central PMCID: PMC8476180.
2020
Wiedemann GM, Geary CD, Lau CM**, Sun JC**. Cutting Edge: STAT1-Mediated Epigenetic Control of Rsad2 Promotes Clonal Expansion of Antiviral NK Cells. J Immunol. 2020 Jul 1;205(1):21-25. doi: 10.4049/jimmunol.2000086. Epub 2020 May 27. PubMed PMID: 32461239; PubMed Central PMCID: PMC7314649.
2018
Lau CM, Adams NM, Geary CD, Weizman OE, Rapp M, Pritykin Y, Leslie CS, Sun JC. Epigenetic control of innate and adaptive immune memory. Nat Immunol. 2018 Sep;19(9):963-972. doi: 10.1038/s41590-018-0176-1. Epub 2018 Aug 6. PubMed PMID: 30082830; PubMed Central PMCID: PMC6225771.
Lau CM*, Tiniakou I*, Perez OA, Kirkling ME, Yap GS, Hock H, Reizis B. Transcription factor Etv6 regulates functional differentiation of cross-presenting classical dendritic cells. J Exp Med. 2018 Sep 3;215(9):2265-2278. doi: 10.1084/jem.20172323. Epub 2018 Aug 7. PubMed PMID: 30087163; PubMed Central PMCID: PMC6122974.
2017
Rapp M*, Lau CM*, Adams NM*, Weizman OE, O'Sullivan TE, Geary CD, Sun JC. Core-binding factor β and Runx transcription factors promote adaptive natural killer cell responses. Sci Immunol. 2017 Dec 8;2(18). doi: 10.1126/sciimmunol.aan3796. PubMed PMID: 29222089; PubMed Central PMCID: PMC6265048.
2016
Lau CM, Nish SA, Yogev N, Waisman A, Reiner SL, Reizis B. Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses. J Exp Med. 2016 Mar 7;213(3):415-31. doi: 10.1084/jem.20150642. Epub 2016 Feb 22. PubMed PMID: 26903243; PubMed Central PMCID: PMC4813676.
Reviews
2022
Lau CM**, Wiedemann GM, Sun JC**. Epigenetic regulation of natural killer cell memory. Immunol Rev. 2022 Jan;305(1):90-110. doi: 10.1111/imr.13031. Epub 2021 Dec 14. Review. PubMed PMID: 34908173; PubMed Central PMCID: PMC8955591.
2018
Lau CM, Sun JC. The widening spectrum of immunological memory. Curr Opin Immunol. 2018 Oct;54:42-49. doi: 10.1016/j.coi.2018.05.013. Epub 2018 Jun 11. Review. PubMed PMID: 29902670; PubMed Central PMCID: PMC6196110.
Collaborations
Check out these great projects with other groups:
2023
Schuster IS, Sng XYX, Lau CM, Powell DR, Weizman OE, Fleming P, Neate GEG, Voigt V, Sheppard S, Maraskovsky AI, Daly S, Koyama M, Hill GR, Turner SJ, O'Sullivan TE, Sun JC, Andoniou CE, Degli-Esposti MA. Infection induces tissue-resident memory NK cells that safeguard tissue health. Immunity. 2023 Mar 14;56(3):531-546.e6. doi: 10.1016/j.immuni.2023.01.016. Epub 2023 Feb 10. PubMed PMID: 36773607; PubMed Central PMCID: PMC10360410.
2022
Imianowski CJ, Whiteside SK, Lozano T, Evans AC, Benson JD, Courreges CJF, Sadiyah F, Lau CM, Zandhuis ND, Grant FM, Schuijs MJ, Vardaka P, Kuo P, Soilleux EJ, Yang J, Sun JC, Kurosaki T, Okkenhaug K, Halim TYF, Roychoudhuri R. BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis. J Exp Med. 2022 Dec 5;219(12). doi: 10.1084/jem.20211476. Epub 2022 Sep 30. PubMed PMID: 36178457; PubMed Central PMCID: PMC9529614.
2021
Sottile R, Panjwani MK, Lau CM, Daniyan AF, Tanaka K, Barker JN, Brentjens RJ, Sun JC, Le Luduec JB, Hsu KC. Human cytomegalovirus expands a CD8+ T cell population with loss of BCL11B expression and gain of NK cell identity. Sci Immunol. 2021 Sep 24;6(63):eabe6968. doi: 10.1126/sciimmunol.abe6968. Epub 2021 Sep 24. PubMed PMID: 34559552; PubMed Central PMCID: PMC8601152.
2020
Holmes TD, Pandey RV, Helm EY, Schlums H, Han H, Campbell TM, Drashansky TT, Chiang S, Wu CY, Tao C, Shoukier M, Tolosa E, Von Hardenberg S, Sun M, Klemann C, Marsh RA, Lau CM, Lin Y, Sun JC, Månsson R, Cichocki F, Avram D, Bryceson YT. The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation. Sci Immunol. 2021 Mar 12;6(57). doi: 10.1126/sciimmunol.abc9801. PubMed PMID: 33712472; PubMed Central PMCID: PMC8274449.
Yewdell WT, Kim Y, Chowdhury P, Lau CM, Smolkin RM, Belcheva KT, Fernandez KC, Cols M, Yen WF, Vaidyanathan B, Angeletti D, McDermott AB, Yewdell JW, Sun JC, Chaudhuri J. A Hyper-IgM Syndrome Mutation in Activation-Induced Cytidine Deaminase Disrupts G-Quadruplex Binding and Genome-wide Chromatin Localization. Immunity. 2020 Nov 17;53(5):952-970.e11. doi: 10.1016/j.immuni.2020.10.003. Epub 2020 Oct 23. PubMed PMID: 33098766; PubMed Central PMCID: PMC8356774.
* co-first author
** co-corresponding author